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If diagnostic imaging is relevant (for example, to assess joint structure), we may review existing X-rays or MRI reports or recommend imaging before finalizing a plan

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A 1200 mg/day ibuprofen dose (20 mg/kg/day, assuming an average human weight of 60 kg), would correspond to a treatment of 246.9 mg/kg/day in mice using the dose translation equation (Human equivalent dose (HED) = Animal Dose (mg/kg) Animal Km (3 for mouse)/Human Km (37 for human) 16